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Introduction:18-Crown-6, also known as crown ether, belongs to macrocyclic ether organic compounds. Its main purpose is high-efficiency phase transfer catalyst for fine organic synthesis, complexing agent, and Chemicalbook extractant for separation and extraction of precious metals and rare earth elements. 
It can be used for the enrichment, separation and masking of ions in chemical analysis. It can also be used in the fields of medicine, biochemistry and electronics industry as ion conductive materials and liquid crystal display element production materials.

Application:One of the most important features of 18-Crown-6 is that they can form stable complexes with various metal salts, ammonium salts, and organic cation compounds.Using this property, various salts can be dissolved in organic solvents.18-Crown-6 can chelate cations into the ring, and at the same time it can form complexes due to the outwardly facing organic genes, and it can also be soluble in non-polar organic solvents. At this time, the unsolvated anion exists in the solvent in the form of a naked anion, so it is extremely active. 18-Crown-6 can dissolve alkali metals and organic alkali metal compounds in organic solvents. Therefore, it has found a wide range of applications in organic synthesis, optical resolution, heavy metal chelation, separation, analysis, and physiologically active medicine and biochemistry. For example, is used as a phase transfer catalyst, so that many reactions that are difficult to react under traditional conditions or even do not occur can be carried out smoothly. This type of reaction has a fast rate, simple conditions, convenient operation and high yield. For example, the yield of the condensation reaction of benzoin in an aqueous solution is extremely low. If 7% of 18-crown-6 is added to the aqueous solution, a 78% yield of benzoin can be obtained.This reaction can also be carried out in benzene (or acetonitrile). Although potassium cyanide is insoluble in benzene, if 18-crown-6 is added, not only the reaction can occur, but the yield can be as high as 95%. Toxicity of 18-crown-6: The oral lethal dose of rats is 300 mg/kg.

Category:Organic building blocks; ethers; general reagents; crown ether series; quaternary ammonium salts; phase transfer catalysts; catalysts; catalysts and additives; ethers; organic raw materials; cyclic crown ethers; fine chemicals; chemical reagents; chemical intermediates;Organic chemical raw materials; biochemical reagents-other chemical reagents; chemical intermediates;other raw materials; API intermediates;Crown Ethers;Macro cycles for Host-Guest Chemistry;crown ether;Miscellaneous Reagents;catalyst;Intermediates;Raw materials; Basic raw materials;Raw materials;Main products; Chemical intermediates Industrial raw materials;  organic chemistry; chemical raw materials; pharmaceutical raw materials.